Nuclear Magnetic Resonance a Compass to Nanoworld
Ref. 54002
- Duration: 9 weeks
- Effort: 27 hours
- Pace: ~3 hours/week
- Languages: English
Description
Nuclear Magnetic Resonance (NMR) phenomenon is currently exploited for many purposes, including medical imaging using the MRI technique but also the characterization of the structure and the dynamics of matter at atomic scale by NMR spectroscopy, which is a key tool in chemistry, structural biology, pharmacology and material sciences. NMR is also employed for oil exploration or the inspection of artworks.
This online course, entitled Nuclear Magnetic Resonance, a compass for the nanoworld, aims at providing students and professionals the basic knowledge about Nuclear Magnetic Resonance (NMR) and an overview of its applications. With the aim of developing the subject from the beginning, this course sets out the fundamental principles of NMR. At the end of the course, you will know about the commonly used NMR experiments and the interpretation of the NMR spectra of solutions and solids. This course will notably highlight the usefulness of NMR spectroscopy for the characterization of organic molecules, proteins, sugars and advanced materials.
This course is intended for undergraduate and graduate students as well as educators and professionals who want to learn the basic concepts of NMR and discover its major applications. This multi-disciplinary course will appeal to students and professionals with background in chemistry, physics, material sciences, pharmacology, medicine and Earth sciences. .
Prerequisites
Students should have a background in basic chemistry, including: (i) the atoms, the elements and the periodic table; (ii) the structure of organic molecules (functional groups, stereochemistry); as well as in basic physics, including some knowledge about the spectroscopy (energy levels, photon, frequency) and the magnetism
Course plan
- Week 1: Importance of NMR and the basic principles of NMR spectroscopy.
- Week 2: NMR experiment and 1H NMR of organic molecules in solution.
- Week 3: Probing covalent bonds and connectivities in organic molecules via J-couplings.
- Week 4: 13C NMR of organic molecules in solution.
- Week 5: 2D NMR of organic molecules in solution and NMR of proteins.
- Week 6: A practical work of liquid-state NMR and NMR of sugars.
- Week 7: Solid-state NMR and the structural study of glasses by NMR.
- Week 8: NMR of catalysts and batteries as well as a practical work of solid-state NMR.
Course team
Olivier Lafon
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Olivier Lafon is professor at the University of Lille and junior member of Institut Universitaire de France (IUF).
Robert Schneider
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Robert Schneider was an assistant professor at the University of Lille, and is currently an NMR application scientist at Bruker Biospin in Fällanden.
Frédérique Pourpoint
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Frédérique Pourpoint is an assistant professor at the Ecole Nationale Supérieure de Chimie de Lille since 2012.Frédérique Pourpoint is an assistant professor at the Ecole Nationale Supérieure de Chimie de Lille since 2012.
Emmanuel Maës
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Emmanuel Maes is a research engineer of CNRS institute and he works in UGSF (“Unité de Glycobiologie Structurale et Fonctionnelle”, i.
Julien Trebosc
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Julien TRÉBOSC is research engineer at Lille 1 University, in charge of a high field NMR spectrometer (800 MHz) since 2005.
Cedric Lion
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Cedric Lion is associate professor at the University of Lille since 2008, specializing in bioorganic chemistry and chemical biology.
Organizations
License
License for the course content
Attribution-NonCommercial
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
License for the content created by course participants
Attribution-NonCommercial
You are free to:
- Share — copy and redistribute the material in any medium or format
- Adapt — remix, transform, and build upon the material
Under the following terms:
- Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.